Image-guided radiotherapy (IGRT) tools and protocols have changed considerably in recent years, with increasing use of volumetric and online IGRT techniques. This event will provide radiotherapy professionals with the information they need to understand best practice in the application of clinical IGRT. Image-guidance protocols for common clinical sites will be discussed and the evolving role of adaptive radiotherapy techniques described.Where daily online IGRT is in use, the accepted methodology for margin calculation can be difficult to apply. We will present the new report from the BIR into this topic, and discuss how residual errors such as delineation error, deformation error, rotational variation, matching error amongst others can be measured and incorporated into a CTV-PTV margin formula.Educational aimsTo understand the basics of operation of common online imaging techniquesTo review the current state of adaptive radiotherapy in clinical practice, and how this may be expected to developTo discuss IGRT protocols for common clinical sitesTo understand recommendations of the BIR geometric uncertainties working party, in particular how to quantify the magnitude of residual geometric uncertainties in daily online IGRTView event programme Registration FeesBIR Member Plan 1 £185BIR Member Plan 2 £125BIR Trainee member £125BIR Retired/Student member £65Non member £295Photography disclaimer The British Institute of Radiology may take photos at events. These images will be used by the BIR to share news about the event and to publicise upcoming events. Images may be used in press releases, printed publicity and published on the website and social media. They will be stored securely, and will be deleted after they are no longer needed for publicity purposes. Please note, by registering for a BIR event you are giving consent for your photo to be used by the BIR for marketing and publicity purposes. If you would prefer not to be photographed, please email the BIR events team or speak to a member of staff on the day.