Description

This course is designed to provide an introduction to genomics and bioinformatics for those working in dermatology and skin biology.

The programme will provide a common understanding of genomics as applied to the skin and update attendees without recent exposure to advances in genetics of the skin. It will focus on genomic technologies including next generation sequencing and bioinformatics analysis. It will provide an overview of the current understanding on monogenic and polygenic skin diseases, and cancer genetics as applied to melanoma and non-melanoma skin cancers. Participants will be exposed to the methods required to analyse large data sets. There will also be a focus on the application of genomics to clinical practice.

The discussion-based course is aimed at practising clinical, academic dermatologists, especially those in training. Applications from clinical lecturers, specialist registrars, consultants and skin biology researchers are also welcome. The course is open to international
participants.

The course is endorsed by The British Association of Dermatologists, Dermatology and Genetic Medicine (BADGEM). This course has been awarded 17 CPD credits by the Royal College of Physicians.

Learning outcomes
Following attendance of this course, participants will be able to:

Explain the basic principles of genetics, gene expression and regulation
Recognise sources of genetic variation in the human genome and how variants are identified
Interpret data generated by genome-wide association studies
Evaluate differential gene expression data and explore visualisation methods for transcriptomic data
Explain how phenotypes arise from genotypes in selected skin diseases
Recognise the impact of genetic mechanisms on therapy development for skin diseases